Eugenol
compus chimic
Eugenolul este un compus organic, un derivat alilic al guaiacolului. Este un compus incolor sau slab gălbui, aromatic și uleios, și se regăsește în uleiurile volatile din anumite specii vegetale, precum: cuișoare, scorțișoară, nucșoară, busuioc și dafin. Denumirea compusului provine de la denumirea științifică a plantei din care se obțin cuișoarele, Eugenia caryophyllata (care este în prezent denumită Syzygium aromaticum).
Eugenolul se utilizează in terapeutica stomatologică.
Este uşor antiseptic, uşor analgezic şi combate hiperamia pulpară.
Stimulează dentinogeneza şi combate inflamaţiile incipiente ale pulpei dentare.
În amestec cu oxidul de zinc se formează eugenatul de zinc care se foloseşte pentru tratamentul plăgii dentare.
Se foloseşte ca material de obturaţie provizorie, obturaţie de canal, pansament gingival, la fixarea de lucrări protetice, etc.
Ovidiu Bojor este un fitoterapeut român, doctor farmacist, membru de onoare al Academiei de Științe Medicale. Este deținător al titlului de Senior Honoris Causa, brevet acordat de către Forumul Președinților Patronatelor din România și Diploma de Merit Academic, acordată de președintele Academiei Române.
compus chimic
Eugenolul este un compus organic, un derivat alilic al guaiacolului. Este un compus incolor sau slab gălbui, aromatic și uleios, și se regăsește în uleiurile volatile din anumite specii vegetale, precum: cuișoare, scorțișoară, nucșoară, busuioc și dafin. Denumirea compusului provine de la denumirea științifică a plantei din care se obțin cuișoarele, Eugenia caryophyllata (care este în prezent denumită Syzygium aromaticum).
Eugenolul se utilizează in terapeutica stomatologică.
Este uşor antiseptic, uşor analgezic şi combate hiperamia pulpară.
Stimulează dentinogeneza şi combate inflamaţiile incipiente ale pulpei dentare.
În amestec cu oxidul de zinc se formează eugenatul de zinc care se foloseşte pentru tratamentul plăgii dentare.
Se foloseşte ca material de obturaţie provizorie, obturaţie de canal, pansament gingival, la fixarea de lucrări protetice, etc.
Ovidiu Bojor este un fitoterapeut român, doctor farmacist, membru de onoare al Academiei de Științe Medicale. Este deținător al titlului de Senior Honoris Causa, brevet acordat de către Forumul Președinților Patronatelor din România și Diploma de Merit Academic, acordată de președintele Academiei Române.
Oil of Cloves: The Benefits of Eugenol
Protect yourself from germs, fungi and infection with antibacterial and anti-inflammatory herbs.
By C. Leigh Broadhurst, Ph.D. and James A. Duke, Ph.D.
May/June 1997
A Sunday ham would be incomplete without a neat array of cloves studding its surface and giving it a spicy flavor. Years ago, however, people used cloves—the dried flower buds of the tropical tree Syzygium aromaticum—more to preserve food than to season it. Clove oil is made up of between 80 to 95 percent eugenol, which is largely responsible for cloves’ ability to keep food from spoiling. Research shows that it offers health benefits to the human body as well.
You may already be familiar with eugenol’s medicinal capacity. Oil of cloves or eugenol is commonly used by dentists because it is antiseptic and anti-inflammatory. They often apply it to the gums to kill germs and relieve the pain of dental surgery such as tooth extractions, fillings, and root canals. Moreover, clove oil, as well as cinnamon, basil, and nutmeg oils—each of which also contain eugenol—are a common ingredient in mouthwashes, toothpastes, soaps, insect repellents, perfumes, foods, and various veterinary medications.
Preliminary research is showing that eugenol may possess additional, more far-reaching medicinal value. For example, some studies show that eugenol fights bacteria and inhibits the growth of many fungi, including Candida albicans, the pathogen responsible for most human yeast infections. In cell cultures, eugenol has been between 1.4 and 2.3 times as effective against C. albicans and C. tropicalis, respectively, as equivalent doses of the antifungal pharmaceutical nystatin. Eugenol or oil of clove is already used to fight fungal infections of the skin, ears, and vagina in some non-Western countries, but this treatment can cause irritation and dermatitis so shouldn’t be tried without the guidance of a health-care practitioner.
Preliminary research also shows that eugenol is a very powerful fat-soluble antioxidant, inhibiting the accumulation of fat peroxide products in red blood cells and maintaining the activities of the body’s antioxidant enzymes at normal levels. Overall results of laboratory studies using animals indicate that only small amounts of eugenol are required for a significant protective effect because eugenol can be directly incorporated into cell membranes, which prevents lipid peroxidation right in place. In one study, rats were poisoned with carbon tetrachloride, which strongly damages tissues by oxidation. Rats who were given eugenol along with the carbon tetrachloride were strongly protected from its toxic effects, according to the researchers.
Finally, preliminary studies show that eugenol protects against cardiovascular disease by inhibiting the aggregation (abnormal clotting) of platelets. In rabbit tests, eugenol prevented aggregation nearly as well as the pharmaceutical indomethacin.
Although cloves are the richest plant source of eugenol, it is also found in significant amounts in allspice, bay rum, greater galangal, basil, nutmeg, turmeric, bay leaf, hyssop, oregano, marjoram, and many other culinary and medicinal plants. Like most essential oils and their major constituents, oil of cloves and eugenol can be toxic at relatively low concentrations when taken internally or when absorbed through the skin (never apply essential oils directly to the skin). Eugenol requires professional supervision to be used internally. Judicious use of fresh or dried herbs and spices containing eugenol is a safer way to consume eugenol, and even small amounts can provide valuable antioxidants.
James Duke, a member of the Herbs for Health Editorial Advisory Board, spent thirty years with the U. S. Department of Agriculture. C. Leigh Broadhurst holds a doctorate in geochemistry and is a nutrition consultant in Clovery, Maryland.
ADDITIONAL READING
Borris, R. P., and J. M. Schaeffer. “Antiparasitic agents from plants”. Phytochemical Resources for Medicine and Agriculture New York: Plenum Press, 1992.
Kurmaravelu, P., et al. “The antioxidant effect of eugenol on CCl4-induced erythrocyte damage in rats”. Nutritional Biochemistry 1996, 7: 23–28.
Laekeman, G.M., et al. “Eugenol a valuable compound for in vitro experimental research and worthwhile for further in vivo investigations”. Phytotherapy Research 1990, 4: 91–96.
Nagababu, E., and N. Lakshmaiah. “Inhibitory effect of eugenol on non-enzymatic lipid peroxidation in rat liver mitochondria”. Biochemical Pharmacology 1992, 43: 2393–2400
| PubChem CID | 3314 |
|---|---|
| Structure | |
| Chemical Safety |  |
| Molecular Formula | C10H12O2 |
| Synonyms | |
| Molecular Weight | 164.2 g/mol |
| Dates |
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Eugenol, also called clove oil, is an aromatic oil extracted from cloves that is used widely as a flavoring for foods and teas and as an herbal oil used topically to treat toothache and more rarely to be taken orally to treat gastrointestinal and respiratory complaints. Eugenol in therapeutic doses has not been implicated in causing serum enzyme elevations or clinically apparent liver injury, but ingestions of high doses, as with an overdose, can cause severe liver injury. Eugenol appears as clear colorless pale yellow or amber-colored liquid. Odor of cloves. Spicy pungent taste. (NTP, 1992) Eugenol is a phenylpropanoid formally derived from guaiacol with an allyl chain substituted para to the hydroxy group. It has a role as an allergen, a plant metabolite, a human blood serum metabolite and a sensitiser. It is a phenylpropanoid, a monomethoxybenzene and a member of phenols. It derives from a guaiacol. | |
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